About Us

Innovation Driven and Patient Centered

Suzhou Puhe Biopharma Co., Ltd.

Suzhou Puhe Biopharma Co., Ltd., established in April 2021, represents a collaborative effort between leading domestic medical enterprises and Shiyu Investment, a fund specializing in the pharmaceutical industry. Our core focus is on the development of innovative small molecule drugs in oncology and supportive cancer care. We aspire to be a pioneering BioPharma company with a base in China and a global reach.

 

 Our strategy is to address distinct clinical needs. That's why we focuses on lung cancer, pancreatic cancer, gastrointestinal tumors and other cancer types with high morbidity and mortality rates worldwide. We employ a strategic approach that combines scientific acumen and industrial foresight. Our methods include introducing and developing innovative drug projects, alongside leveraging various means to expand our development opportunities. We are committed to accelerating the industrialization of our company by integrating resources efficiently.

 

At the heart of our approach are molecular targets, around which we have established a robust platform for developing unique small molecule drugs. This platform integrates advanced technologies like new-generation kinase inhibitors, allosteric inhibitors, synthetic lethality approaches, and Proteolysis targeting chimeras (Protacs) to address complex challenges. Our capabilities span a wide range, from target discovery and molecular structure design to in vivo and in vitro activity assessments, safety and pharmacokinetics evaluations, regulatory submissions, and the initiation of clinical trials across phases I, II, and III, culminating in product production.

2021 2021

Year of establishment

50 89 +

Number of patent applications

10 11 +

Patents Granted

5 5

Preclinical Product Pipeline

3 4

Clinical Product Pipeline

Development History
2021

Apr.Company founded

4 products in-licensed, including PH001 (YK-029A)

May.PH001 clinical phase I investigator meeting launched

Aug.PH001 first exon20ins patient enrolled

2022

Sept.PH001 received CDE breakthrough therapy certification

2023

Jan.PH001 received CDE clinical phase III trial approval

PH002 received FDA clinical phase Ib approval

PH005 received CDE clinical approval

Mar.5 patents granted and 47 independent research and development project patents submitted

Apr.Selected into AACR

PH020 oral presentation

PH009 exhibited on poster

May.PH001 clinical phase III investigator meeting launched

Jun.Selected into ASCO

PH001 discussed on poster

2024

Jun.PH009 received CDE clinical phase I trial approval

PH002 completed phase IIb trial enrollment

Company Layout
Based in China, Embracing the World
Activated In progress
Beijing
Beijing

Operation Center
Project Management Center

Suzhou
Suzhou

R&D Center
Innovative Preparation Production Center

Henan
Henan

API Production Base
Topical Preparation Production Base

Shanghai
Shanghai

Business Development/Clinical
Innovation Platform

California
California

Overseas Clinical/Business Development
Innovation Platform

New York
New York

Overseas Clinical/Business Development
Innovation Platform

Beijing Suzhou Henan Shanghai California New York
Beijing

Operation Center
Project Management Center

Suzhou

R&D Center
Innovative Preparation Production Center

Henan

API Production Base
Topical Preparation Production Base

Shanghai

Business Development/Clinical
Innovation Platform

US East

Overseas Clinical/Business Development
Innovation Platform

New York

Overseas Clinical/Business Development
Innovation Platform