Suzhou Puhe Biopharma Co., Ltd., established in April 2021, represents a collaborative effort between leading domestic medical enterprises and Shiyu Investment, a fund specializing in the pharmaceutical industry. Our core focus is on the development of innovative small molecule drugs in oncology and supportive cancer care. We aspire to be a pioneering BioPharma company with a base in China and a global reach.
Our strategy is to address distinct clinical needs. That's why we focuses on lung cancer, pancreatic cancer, gastrointestinal tumors and other cancer types with high morbidity and mortality rates worldwide. We employ a strategic approach that combines scientific acumen and industrial foresight. Our methods include introducing and developing innovative drug projects, alongside leveraging various means to expand our development opportunities. We are committed to accelerating the industrialization of our company by integrating resources efficiently.
At the heart of our approach are molecular targets, around which we have established a robust platform for developing unique small molecule drugs. This platform integrates advanced technologies like new-generation kinase inhibitors, allosteric inhibitors, synthetic lethality approaches, and Proteolysis targeting chimeras (Protacs) to address complex challenges. Our capabilities span a wide range, from target discovery and molecular structure design to in vivo and in vitro activity assessments, safety and pharmacokinetics evaluations, regulatory submissions, and the initiation of clinical trials across phases I, II, and III, culminating in product production.
Year of establishment
Number of patent applications
Patents Granted
Preclinical Product Pipeline
Clinical Product Pipeline
Apr.Company founded
4 products in-licensed, including PH001 (YK-029A)
May.PH001 clinical phase I investigator meeting launched
Aug.PH001 first exon20ins patient enrolled
Sept.PH001 received CDE breakthrough therapy certification
Jan.PH001 received CDE clinical phase III trial approval
PH002 received FDA clinical phase Ib approval
PH005 received CDE clinical approval
Mar.5 patents granted and 47 independent research and development project patents submitted
Apr.Selected into AACR
PH020 oral presentation
PH009 exhibited on poster
May.PH001 clinical phase III investigator meeting launched
Jun.Selected into ASCO
PH001 discussed on poster
Jun.PH009 received CDE clinical phase I trial approval
PH002 completed phase IIb trial enrollment
Operation Center
Project Management Center
R&D Center
Innovative Preparation Production Center
API Production Base
Topical Preparation Production Base
Business Development/Clinical
Innovation Platform
Overseas Clinical/Business Development
Innovation Platform
Overseas Clinical/Business Development
Innovation Platform
Operation Center
Project Management Center
R&D Center
Innovative Preparation Production Center
API Production Base
Topical Preparation Production Base
Business Development/Clinical
Innovation Platform
Overseas Clinical/Business Development
Innovation Platform
Overseas Clinical/Business Development
Innovation Platform