Business Development

Our product pipelines are highly differentiated and globally competitive

R&D System
Differentiated Project Initiation
We conduct a meticulous assessment of unmet clinical needs and market competition, both domestically and internationally, to launch projects with distinct differentiation in targets and technologies. We focus primarily on cancers with high incidence and mortality rates, immunological disorders, and metabolic diseases.
Technology Innovation
By integrating emerging technologies, such as next-generation kinase inhibitors, allosteric inhibition, synthetic lethality, PROTACs, and molecular glues, and based on well-defined mechanisms and high selectivity, we are committed to delivering potential drugs with superior efficacy and lower toxicity for clinical applications.
Platform System
Powered by AI technology, we maximize the reduction of development costs and the improvement of efficiency, and through a flexible and innovative operational model, we efficiently advance the development of our pipelines.
Product Pipelines
Drug Type Pipeline Code Target Indication Lead Compound PCC Preclinical IND Phase I Phase II Phase III
EGFR mutation
PH001
EGFR
NSCLC exon20ins
PH001
EGFR
NSCLC PACC
PH009
EGFR
C797S/T790M/19Del/L858R
NSCLC
PH039
pan-EGFR
NSCLC
Synthetic Lethality
PH020
PRMT5
Solid tumors with
MTAP del
Licensed to Bayer
PH027
WRN
Solid tumors with
MSI-H
PH050
/
Solid tumors
PROTACs
/
Molecular glues
PH051
/
Immunological
PH033
/
Solid tumors
Others
PH030
/
Metabolic diseases
PH056
/
Metabolic diseases
Patient Recruitment
Recruiting non-small cell lung cancer patients with
EGFR exon20ins
Indications: Advanced or metastatic non-small cell lung cancer with EGFR exon 20 insertion mutation that has not received prior systemic anti-tumor therapy
Investigational drug: YK-029A tablets (Project PH001)
Age requirement: 18-75 years old (including boundary values)
Number of recruited subjects: no preset limit
Region: Anhui/ Beijing/ Fujian/ Gansu/ Guangdong/ Guangxi/ Guizhou/ Hebei/ Heilongjiang/ Henan/ Hubei/ Hunan/ Jiangsu/ Jiangxi/ Jilin/ Liaoning/ Shandong/ Shanghai/ Shanxi/ Shaanxi/ Sichuan/ Tianjin/ Xinjiang/ Yunnan/ Zhejiang/ Chongqing
Patient Recruitment
Recruiting non-small cell lung cancer patients with EGFR mutations
Indications: Advanced or metastatic non-small cell lung cancer with EGFR mutations
Investigational drug: PH009-1 tablets
Age requirement: >18 years old
Number of recruited subjects: no preset limit
Region: Guangdong/ Henan/ Shandong/ Tianjin/ Fujian/ Guangxi/ Hubei/ Shanghai/ Hunan/ Heilongjiang